Yaami was 20 when she moved to Mumbai to pursue a career in movies. She made her television debut with Chand Ke Paar Chalo, she also participated in the reality shows Meethi Choori No.1 and Kitchen Champion Season 1.
She made her film debut in Kannada film Ullasa Utsaha. Gautam later made her Bollywood debut with Vicky Donor, in which she starred opposite Ayushmann Khurrana. She played the role of Bengali girl Ashima Roy, a girl who falls in love with a Punjabi boy with a past. Despite its small budget, the movie became a major commercial success and received critical appreciation .Though after getting a lot of awards for her film Yaami Gautam is on clouds, As she have already signed her second film which will be directed by Neeraj pandey opposite Ali zafar, yaami has got her third film with an actor she always adored Sharman Joshi.Yaami is really excited to pair with Sharman and looking forward for the shoot to start