Published On : Sun, Feb 25th, 2018

Sri Devi’s Untimely Death: It’s time to dedicate the knowledge about heart disease in women to her

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25th February 2018: RIP Heart Care Foundation and NCD cell of IMA, condones the untimely death of Padma Shri Awardee Ms Sri Devi and dedicate a special campaign about prevention of sudden cardiac death among women. In 1999 she released health messages regarding prevention of heart disease.

Sudden cardiac death in women

A 38-year follow-up from the Framingham Heart study evaluated the incidence of sudden cardiac death in women compared with men

1. Women had a lower SCD rate than men at all ages

2. The risk of sudden death among women with coronary heart disease is one-half that of men with coronary heart disease

3. A higher fraction of sudden deaths in women occur in the absence of prior overt coronary heart disease (63 versus 44 percent in men).

4. The presence of heart failure increases overall mortality and the incidence of SCD

5. However, among patients with heart failure the absolute risk in women is only one-third that of men.

6. Phobic anxiety is associated with an increased risk of SCD in women. Some, but not all, of this risk can be ascribed to CHD risk factors associated with phobic anxiety such as diabetes, hypertension, and elevated serum cholesterol.

Heart attack: women vs men

It is more difficult to establish the diagnosis of heart disease in women

Women generally present about 10 years later than men

Women present with a greater risk-factor burden.

Women are less likely than men to have typical angina

Women who present to the emergency room with new onset chest pain are approached and diagnosed less aggressively than men.

Women have more chances to present with angina than heart attack but when they present with heart attack it is more fatal

Many cases of heart attack in women go unrecognized, particularly at younger ages or in patients with diabetes.

All women with intermediate or higher risk shoyld be evaluated.

Treadmill exercise testing has a higher false-positive rate in women (for the diagnosis of obstructive coronary artery disease)

The prevalence of significant coronary disease found at the time of angiography is lower in women than men presenting with chest pain.

Most women with chest pain and no evidence of blockages on coronary angiography have cardiac syndrome X or microvascular disease, or far more rarely, takotsubo cardiomyopathy or coronary dissection. [uptodate]

Screening for heart disease

1, Six minutes walk test: if you can walk more than 500 meters in six minutes you do not have significant blockages or if you can walk 2 km or climb two flight of stairs you do not have significant blockages

2. Never ignore unexplained weakness, tiredness, first onset chest burning or first onset breathlessness after he age of 40

3. If any member of your family male had heart disease before 55 or female before 65, it amounts to strong family history

4. It will be a strong family history for Sri Devi family for future generations if her SCD is linked to blockages in the heart

What to do in sudden cardiac death

1. Sudden cardiac arrest (SCA) and sudden cardiac death (SCD) refer to the sudden cessation of organized cardiac electrical activity

2. The event is referred to as SCA (or aborted SCD) if an intervention (eg, CPR, defibrillation, cardioversion, anti-arrhythmic drug) or spontaneous reversion restores circulation. The event is called SCD if the patient dies.

3. The exact mechanism of collapse in an individual patient is often impossible to establish since, for the vast majority of patients who die suddenly, cardiac electrical activity is not being monitored at the time of their collapse.

4. However, in studies of patients who were having cardiac electrical activity monitored at the time of their event, ventricular tachycardia (VT) or ventricular fibrillation (VF) (very fats irregular heart beat) accounted for the majority of episodes, with bradycardia or asystole (no heart beat) accounting for nearly all of the remainder.

5. In most patients with VT/VF, sustained ventricular arrhythmia is preceded by an increase in ventricular ectopy and the development of repetitive ventricular arrhythmia, particularly runs of non-sustained VT.

6. There are many cardiac and non-cardiac causes for a sustained ventricular tachy-arrhythmia that can result in SCD. Among all SCD in all age groups, the majority (65 to 70 percent) are related to coronary heart disease, with other structural cardiac disease (approximately 10 percent), arrhythmias (irregular heart beat) in the absence of structural heart disease (5 to 10 percent), and non-cardiac causes (15 to 25 percent) responsible for the remaining deaths.

7. Start CPR 10 in all cases of sudden cardiac arrest and continue till medical help arrives along with external electric shock machine.

8. It may be advisable to opt for virtual autopsy along with blood molecular tests in cases of sudden cardiac death to know chances of similar episode in the family in future.

Dr KK Aggarwal – President heart Care Foundation of India and Immediate Past National President IMA