Nagpur: A Continuing Medical Education Programme (CME) was organised at a city hotel recently. Dr Shankar Khobragade was the keynote speaker. The session was presided over by Dr R B Kalamkar and Dr Sanjay Jain and attended largely by medical fraternity of the city.
Dr Shankar Khobragade pointed out that as per WHO, every year 16.6 million people die due to Cardio Vascular Disease (CVD) and it contribute to 1/3rd of global deaths. He further pointed out that Indians have high prevalence of low HDL cholesterol. This appears to be the part of Asian Indian phenotype, which includes increased plasma insulin levels, insulin resistance, increase waist circumference, excess visceral fat and low adiponectin levels.
On managing dyslipidemia, Dr Khobragade said Statins play important role in reducing LDL C 18 to 55 per cent, increase HDL C by 5 to 15 per cent and reduce triglycerides by 7 to 30 per cent.
Insignificantly a few patients have shown adverse reactions like myopathy, rhabdomyolisis elevation of serum aminotransferase activity. He listed various statins available in the market and gave top rank to Rosuvastatin and Atorvastatin and also gave comparative studies from various trials and studies about safety and efficacy.
In the end interactive discussion was held with the audience and their doubts cleared.